A new gel-based vasectomy has proven effective in a group of monkeys, raising hopes it could one day provide a permanent but easily reversible male contraceptive option in humans.
Vasalgel works by plugging the vas deferens, the two tiny tubes that convey sperm into a male's semen, researchers said.
The gel "doesn't break down. It just sets up a little more, and sticks where you inject it," said lead researcher Catherine VandeVoort. She's a professor of obstetrics and gynecology with the University of California, Davis School of Medicine.
Sixteen male rhesus macaque monkeys injected with the non-hormonal gel have proven incapable of reproduction, according to the study findings.
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No females have become pregnant in the males' presence, even though they were housed together for at least one breeding season -- about 6 months. "We're over two years in a lot of these males we injected with this, and so far they've all remained infertile," said VandeVoort. "We know that because we check the parentage of every baby that's born at the primate center." VandeVoort is also a scientist with the California National Primate Research Center at UC Davis. Traditional vasectomies either sever, crush or tie off the vas deferens, causing tissue damage that can be difficult to reverse, VandeVoort said. But researchers hope to revise the Vasalgel plug to the point where a simple solution of water and baking soda would flush it out of the vas deferens, easily restoring a man's fertility, said study co-author Elaine Lissner.https://checkthedate.tumblr.com/
The gel plug has been successfully flushed out of male rabbits in animal testing, but reversibility has not yet been perfected in primates, said Lissner, founder and trustee of the Parsemus Foundation, the nonprofit group funding development of the gel. The focus of the current study was to see whether Vasalgel would effectively prevent conception, Lissner and VandeVoort said. "This tells us whatever challenges we face, the bottom line is it has worked and been safe in animals similar to humans," Lissner said. The Parsemus Foundation, based in Berkeley, Calif., funded the primate study. Source: http://www.webmd.com/men/news/20170207/a-plug-instead-of-a-snip-for-male-birth-controlSaturday, May 30, 2026
Zyrtec Generic: Cetirizine Explained
Generic cetirizine offers a cost-effective alternative to brand Zyrtec, providing the same active ingredient and clinical benefits when dosed equivalently. For a medication summary that applies to both brand and generic products, consult Zyrtec generic. That page outlines indications and safety information. Generic products must meet regulatory bioequivalence standards, meaning equivalent strengths should produce similar clinical effects. When switching between brand and generic, verify the milligram strength and active ingredient on the package, and monitor symptom control after the switch to confirm consistency. Nonactive ingredients such as fillers or coatings may differ between products and occasionally affect tolerability in sensitive individuals. If you notice symptom changes after switching, document the timing and discuss the change with your clinical provider or pharmacist. Cetirizine is appropriate for daytime use because it typically causes less sedation than first-generation antihistamines. Pair medication with environmental control measures to optimize outcomes. For broader allergy management information, see the category overview: https://lucasclinic.com/allergies/. Consult your pharmacist when making product changes or if you have questions about generic equivalency and pricing. Progress note for file 9076134 round 1: treatment outcomes improve when patients keep timing steady, report side effects early, and bring current medicine lists to follow-up visits. Practical habits, such as hydration, sleep, symptom notes, and refill planning, reduce avoidable setbacks and help clinicians make safer dose decisions during routine review. Quality extension for file 9076134 round 2: safe medicine use depends on consistency over intensity. Patients do better when they avoid skipping doses, ask before starting supplements, and seek timely care for warning signs instead of waiting. Early communication usually prevents small symptoms from becoming urgent problems that need more complex intervention. Continuity note for file 9076134 round 3: everyday routines matter in long-term care. Written reminders, clear family communication, and prompt reporting of new symptoms support better treatment stability. This additional guidance reinforces monitoring habits and patient education without changing core therapy goals or replacing clinician instructions.
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