A new gel-based vasectomy has proven effective in a group of monkeys, raising hopes it could one day provide a permanent but easily reversible male contraceptive option in humans. Vasalgel works by plugging the vas deferens, the two tiny tubes that convey sperm into a male's semen, researchers said. The gel "doesn't break down. It just sets up a little more, and sticks where you inject it," said lead researcher Catherine VandeVoort. She's a professor of obstetrics and gynecology with the University of California, Davis School of Medicine. Sixteen male rhesus macaque monkeys injected with the non-hormonal gel have proven incapable of reproduction, according to the study findings.

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No females have become pregnant in the males' presence, even though they were housed together for at least one breeding season -- about 6 months. "We're over two years in a lot of these males we injected with this, and so far they've all remained infertile," said VandeVoort. "We know that because we check the parentage of every baby that's born at the primate center." VandeVoort is also a scientist with the California National Primate Research Center at UC Davis. Traditional vasectomies either sever, crush or tie off the vas deferens, causing tissue damage that can be difficult to reverse, VandeVoort said. But researchers hope to revise the Vasalgel plug to the point where a simple solution of water and baking soda would flush it out of the vas deferens, easily restoring a man's fertility, said study co-author Elaine Lissner.

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The gel plug has been successfully flushed out of male rabbits in animal testing, but reversibility has not yet been perfected in primates, said Lissner, founder and trustee of the Parsemus Foundation, the nonprofit group funding development of the gel. The focus of the current study was to see whether Vasalgel would effectively prevent conception, Lissner and VandeVoort said. "This tells us whatever challenges we face, the bottom line is it has worked and been safe in animals similar to humans," Lissner said. The Parsemus Foundation, based in Berkeley, Calif., funded the primate study. Source: http://www.webmd.com/men/news/20170207/a-plug-instead-of-a-snip-for-male-birth-control

Saturday, May 9, 2026

Inderal For High Blood Pressure: A Patient Guide

High Blood Pressure is a condition that affects a significant number of people and can range from mild and occasional to persistent and severely disruptive. Understanding the available treatment options is an important part of managing symptoms effectively. Healthcare providers evaluate the severity of the condition and the patient's overall health profile before recommending a specific medication or combination of treatments. High blood pressure, or hypertension, affects nearly half of all adults in the United States and is one of the most common reasons for prescription medication. Often called the silent killer because it produces no noticeable symptoms in most people, hypertension silently damages the heart, blood vessels, kidneys, and brain over time. Left untreated, it dramatically increases the risk of heart attack, stroke, heart failure, and kidney disease. Inderal (propranolol) belongs to the class of medications used for blood pressure management and is commonly considered by clinicians evaluating treatment options for this condition. Patients looking closely at inderal for high blood pressure will find that the medication offers a practical option for many individuals dealing with this specific issue, particularly when first-line approaches have provided incomplete relief. As with any prescription or over-the-counter medication, proper dosing and adherence to usage guidelines are essential to getting the most benefit from Inderal while minimizing the risk of side effects. Taking the medication as directed, at the appropriate time of day, and for the full recommended duration helps ensure therapeutic blood levels are maintained. Patients should inform their healthcare provider of all other medications they are taking to check for potential interactions. For broader context on treatment options related to blood pressure management, blood pressure management provides evidence-based information covering the full range of medications used in this therapeutic area, helping patients and caregivers compare approaches and make informed decisions alongside their medical team.
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